国家级青年人才项目入选者，中山大学“百人计划”引进人才，博士和硕士研究生导师，美国肝脏病学研究学会（AASLD）会员。研究方向：运用临床数据人工智能分析、生物信息学和3D培养类器官实验生物学等交叉学科干湿结合手段，研究肝脏损伤修复再生机制、肝脏胆管疾病的分子标志物、病理机制和治疗方法。此外，课题组还致力于泛癌症、衰老和端粒调控网络的生物信息人工智能多组学分析。多项代表作发表于Hepatology（2025、2023）、Aging Cell (2025)、eBioMedicine（2024）、Nucleic Acids Research（2023）、Briefings in Bioinformatics（2021）等国际知名SCI期刊杂志。主持多项国家自然科学基金和广东省自然基金项目。

1. Man-Huan Xiao#, Dong Ma#, Sihan Wu#, Zaoli Huang#, Peishi Liang, Huadong Chen, Zhihai Zhong, Wei Li, Fen Wang, Yanlai Tang, Juncheng Liu, Hong Jiang*, Xuyang Feng*, Zhenhua Luo*. Integrative single-cell and spatial transcriptomic analyses identify a pathogenic cholangiocyte niche and TNFRSF12A as therapeutic target for biliary atresia.（2025）Hepatology. Apr 1;81(4):1146-1163.
2. Yina Lan, Xiaole Liang, Guotao Kuang, Tengfei Ma, Fangyingnan Zhang, Zaoli Huang, Huan Wang*, Zhenhua Luo*, Xuyang Feng*. STN1 Shields CTC1 From TRIM32-Mediated Ubiquitination to Prevent Cellular Aging. (2025) Aging Cell. 24(11):e70214.
3. Man-Huan Xiao, Sihan Wu, Peishi Liang, Dong Ma, Jiang Zhang, Huadong Chen, Zhihai Zhong, Juncheng Liu, Hong Jiang*, Xuyang Feng*, Zhenhua Luo*. Mucosal-associated invariant T cells promote ductular reaction through amphiregulin in biliary atresia. (2024) eBioMedicine. 103:105138 
4. Abigail E Russi#, Pranavkumar Shivakumar#, Zhenhua Luo*, Jorge A Bezerra*. Plasticity between type 2 innate lymphoid cell subsets and amphiregulin expression regulates epithelial repair in biliary atresia. (2023) Hepatology. 78(4):1035-1049
5. Huan Wang#, Tengfei Ma#, Xiaotong Zhang, Wei Chen, Yina Lan, Guotao Kuang, Shih-Jui Hsu, Zibin He, Yuxi Chen, Jason Stewart, Anukana Bhattacharjee, Zhenhua Luo*, Carolyn Price*, Xuyang Feng*. CTC1 OB-B interaction with TPP1 terminates telomerase and prevents telomere overextension. (2023) Nucleic Acids Research. 51(10):4914-4928
6. Huiya Xu, Wei Li, Chongmei Zhu, Na Cheng, Xiaoxia Li, Fengyun Hao, Junfeng Zhu, Liyun Huang, Ran Wang, Liantang Wang*, Zhenhua Luo*, Fen Wang*. Proteomic profiling identifies novel diagnostic biomarkers and molecular subtypes for mucinous tubular and spindle cell carcinoma of the kidney. (2022) Journal of Pathology. 257(1):53-67.
7. Zhenhua Luo#, Pranavkumar Shivakumar#, Reena Mourya, Sridevi Gutta and Jorge A. Bezerra. Gene expression signatures associated with survival times of pediatric patients with biliary atresia identify potential therapeutic agents. (2019) Gastroenterology. 157(4)：1138-1152 
8. Zhenhua Luo, Anil G Jegga and Jorge A. Bezerra. Gene-disease associations identify a connectome with shared molecular pathways in human cholangiopathies. (2018) Hepatology. 67: 676-689. doi:10.1002/hep.29504
9. Zhenhua Luo#, Weixu Wang#, Feng Li#, Zhou Songyang, Xuyang Feng, Changchang Xin, Zhiming Dai* and Yuanyan Xiong*. Pan-cancer analysis identifies telomerase-associated signatures and cancer subtypes. (2019) Molecular Cancer. 18(1):106.
10. Zhenhua Luo, Weijin Liu, Panpan Sun, Feng Wang, Xuyang Feng. Pan-cancer analyses reveal regulation and clinical outcome association of the shelterin complex in cancer. (2021) Briefings in Bioinformatics. Bbaa441 
11. Zhenhua Luo, Xuyang Feng, Haoli Wang, Weiyi Xu, Yong Zhao, Wenbin Ma, Dan Liu, Songshan Jiang, Junjiu Huang* and Zhou Songyang*. MiR-23a induces telomere dysfunction and cellular senescence by inhibiting TRF2 expression. (2015) Aging Cell 14(3): 391–399. 

1. 美国肝脏病学研究学会研究奖

2. Gastroenterology、Liver international等杂志审稿人