
中山大学“百人计划”青年学术骨干,副研究员,硕士生导师。曾在荷兰格罗宁根大学医学中心长期从事炎症性肠病和其他复杂疾病研究工作,整合基因组,转录组,蛋白组,代谢组,微生物组等多组学挖掘疾病分子标记物和潜在机制。近三年代表作发表在Nature Genetics (IF=38.33), Gut (IF=23.06), Science Translational Medicine (IF=17.96), Nature Communications (IF=14.92)等国际知名期刊。
研究方向
1. 炎症性肠病的遗传分子机制和生物分子标记物;
2. 宿主-肠道微生物的相互作用对疾病的影响;
1. Hu, S., Vila, A. V., Gacesa, R., Collij, V., Stevens, C., Fu, J. M., ... & Weersma, R. K. (2021). Whole exome sequencing analyses reveal gene–microbiota interactions in the context of IBD. Gut, 70(2), 285-296.
2. Hu, S., Uniken Venema, W. T., Westra, H. J., Vich Vila, A., Barbieri, R., Voskuil, M. D., ... & Weersma, R. K. (2021). Inflammation status modulates the effect of host genetic variation on intestinal gene expression in inflammatory bowel disease. Nature communications, 12(1), 1-10.
3. Bourgonje, A. R.#, Hu, S.#, Spekhorst, L. M., Zhernakova, D. V., Vich Vila, A., Li, Y., ... & Weersma, R. K. (2022). The effect of phenotype and genotype on the plasma proteome in patients with inflammatory bowel disease. Journal of Crohn's and Colitis, 16(3), 414-429.
4. Swarte, J. C.#, Li, Y.#, Hu, S.#, Bj?rk, J., Gacesa, R., ... & Weersma, R. K. (2022). Gut Microbiome Dysbiosis is Associated with Increased Mortality following Solid Organ Transplantation. Science Translational Medicine. In press
5. Lopera-Maya, E. A.#, Kurilshikov, A.#, van der Graaf, A.#, Hu, S.#, Andreu-Sánchez, S., Chen, L., ... & Sanna, S. (2022). Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project. Nature genetics, 54(2), 143-151.
招生招聘
依托中山大学附属第一医院大规模生物样本库和精准医学研究院高性能计算平台,本课题组科研经费充足,课题方向多元。同时与医院临床科室、校内多学科专家、海内外知名实验室有长期深入合作。欢迎对系统生物学和生物信息学有兴趣的同学加入。