2019年毕业于暨南大学获得博士学位（美国俄亥俄州立大学联合培养博士），同年进入中山大学附属第一医院精准医学研究院从事博士后研究工作。2023年转聘为中山大学副研究员。2024年入选中山大学附属第一医院“柯麟新锐”人才计划。主要研究肿瘤细胞信号转导、蛋白质翻译修饰在炎症与免疫中调控作用机制等。代表性论文发表在 Nat Struct Mol Biol, Acta Pharm Sin B, Nat Commu, Nat Chem Biol, Nat Metab, Cancer Res, Mol Cancer等高水平学术期刊。

1. Qiwei Jiang#*, Peipei Song#, Shuishen Zhang#, Qin Ren, Meiyan Zhu, Jiawei Ge, Lang Bu, Wei Chen, Xueji Wu, Shiyao Han, Yaqing Su, Lei Wang, Wei Xie, Chao Cheng, Zhenwei Peng*, Jianping Guo*. TRIM21 and OTUD6A orchestrate AKT K27-linked atypical ubiquitination to modulate cancer chemoresistance. Nature Structural & Molecular Biology. 2025 Sep, In press.

2. Qiwei Jiang#, Yong Li#, Songwang Cai#, Xingyuan Shi#, Yang Yang, Zihao Xing, Zhenjie He, Shengte Wang, Yubin Su, Meiwan Chen, Zhesheng Chen, Zhi Shi*. GLUL stabilizes N-Cadherin by antagonizing β-Catenin to inhibit the progresses of gastric cancer. Acta Pharmaceutica Sinica B. 2024 Feb 14(2):698-711.

3. Qiwei Jiang#; Xiaomei Zhang#; Xiaoming Dai#; Shiyao Han; Xueji Wu; Lei Wang; Wenyi Wei; Ning Zhang; Wei Xie*; Jianping Guo*. S6K1-mediated phosphorylation of PDK1 impairs AKT kinase activity and oncogenic functions. Nature Communications. 2022 Mar 22;13(1):1548.

4. Qiwei Jiang#; Nana Zheng#; Lang Bu#; Xiaomei Zhang; Xiaoling Zhang; Yuanzhong Wu; Yaqing Su; Lei Wang; Xiaomin Zhang; Shancheng Ren; Xiangpeng Dai; Depei Wu; Wei Xie; Wenyi Wei*; Yasheng Zhu*; Jianping Guo*. SPOP-mediated ubiquitination and degradation of PDK1 suppresses AKT kinase activity and oncogenic functions, Molecular Cancer, 2021, 20(1).

5. Lu Gan#, Qiwei Jiang#, Dong Huang#, Xueji Wu, Xinying Zhu, Lei Wang, Wei Xie, Jialuo Huang, Runzhu Fan, Yihang Jing, Guihua Tang, Xiang David Li, Jianping Guo*, Sheng Yin*. A natural small molecule alleviates liver fibrosis by targeting apolipoprotein L2. Nature Chemical Biology. 2025 Jan;21(1):80-90.

6. Xiaoming Dai#; Cong Jiang#; Qiwei Jiang#; Lan Fang; Haihong Yu; Jinhe Guo; Peiqiang Yan; Fangtao Chi; Tao Zhang; Hiroyuki Inuzuka; John M Asara; Ping Wang; Jianping Guo*; Wenyi Wei*. AMPK-dependent phosphorylation of the GATOR2 component WDR24 suppresses glucose-mediated mTORC1 activation. Nature Metabolism. 2023 Feb;5(2):265-276.

1.肿瘤分子生物学教育部重点实验室开放课题, 202505，2025-06至2027-05，主持。

2.国家自然科学基金青年项目，32100559，2022-01至2024-12，主持。

3.广东省自然科学基金面上项目，2023A1515010385，2023-01至2025-12，主持。

4.中国博士后科学基金面上项目，2020M683035，2020-09至2021-10，主持。